Developments in MALDI Mass Spectrometry Could Lead to Advancements in Cancer Imaging Technologies for Anatomic Pathologists and Clinical Laboratories

This may especially benefit cancer research and treatment thanks to MALDI’s ability to provide pathologists with a view of the whole-tissue micro-environment Though it may be years before Matrix-Assisted Laser Desorption Ionization (MALDI) mass spectrometry finds use in clinical applications, recent developments show medical laboratories and anatomic pathologists how one type of technology is being rapidly adapted for use in diagnosing cancers. Richard Drake, PhD, Director of the Medical...

Biomarker Trends Are Auspicious for Pathologists and Clinical Laboratories

Few anatomical tools hold more potential to revolutionize the science of diagnostics than biomarkers, and pathologists and medical laboratories will be first in line to put these powerful tools to use helping patients with chronic diseases There’s good news for both anatomic pathology laboratories and medical laboratories worldwide. Large numbers of clinically-useful new biomarkers continue to be validated and are in development for use in diagnostic tests and therapeutic drugs. Clinical...

Swiss Researchers Use New Mass Spectrometry Technique to Obtain Protein Data, Create Strategy That Could Lead to Clinical Laboratory Advances in Personalized Medicine

Researchers believe they have begun to crack open a ‘black box’ involving the genomes and diseases of individual patients Researchers in Switzerland are developing a new way to use mass spectrometry to explain why patients respond differently to specific therapies. The method potentially could become a useful tool for clinical laboratories that want to support the practice of precision medicine. It is also one more example of how mass spectrometry is being used by researchers to develop new...

Study into Use of Breath Analysis to Monitor Lung Cancer Therapy Enhances Clinical Laboratories’ Ability to Support Precision Medicine

A recent study adds to the growing body of research into breath analysis as a diagnostic and treatment-monitoring tool More progress is being made on the diagnosis and treatment of lung cancer. The newest developments will be of interest to anatomic pathologists who work with lung specimens. A new study suggests it is possible to use breath specimens to monitor the progress of lung cancer patients undergoing therapy. The study was conducted by Inbar Nardi-Agmon, MD, Thoracic Cancer Research...

Researchers at ORNL Blend Microscopy and Mass Spectrometry to Create a Tool That Simultaneously Identifies and Chemically Analyzes Substances

Oak Ridge National Laboratory sees potential for clinical laboratories and pathology groups to control disease and assess treatments What do you get by blending microscopy with mass spectrometry? A new multi-tasking tool for studying disease progression and response to treatments in patients. Combining these two technologies into a single device could also have uses for clinical laboratory scientists and pathologists. However, much research must be done before such a device is ready to obtain...