News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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Mayo Clinic Scientists Use Chemical Analysis of Beethoven’s Hair to Determine Lead Poisoning May Have Contributed to Composer’s Hearing Loss and Other Health Ailments

Results of an earlier study in which locks of Beethoven’s hair underwent genetic analysis showed the composer ‘had a predisposition for liver disease and became infected with hepatitis B’ Here is an example of modern technologies being used with “historical...

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Brigham and Women’s Hospital Researchers Develop Implantable ‘Lab in a Patient’ to Test Effectiveness of Brain Cancer Drugs

Scientists reported positive Phase 1 trial results of their “intratumoral microdevice” in patients with glioma tumors Here is an example of new microtechnology which has the potential to greatly shorten the time and improve the ability of physicians to determine which...

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University of Cincinnati Pathologist Develops Speedier Tissue Processing for Small Biopsies

Syringe-based technique is disposable and enables clinical laboratories to process small biopsies in about two hours instead of overnight and with significantly less waste Histotechnologists and clinical laboratory managers know that the standard method of processing...

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Fred Hutch Researchers Identify Oral Bacteria That Appear to Play a Role in Certain Colon Cancers

Discovery highlights how ongoing microbiome research points to new opportunities that can lead to development of more effective cancer screening clinical laboratory tests New research from the Fred Hutchinson Cancer Center in Seattle once again demonstrates that the...

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UPMC Researchers Develop Biomarkers That Identify Biological Age While Also Predicting Disease Risk

Scientists turned to metabolomics to find cause of biological aging and release index of 25 metabolites that predict healthy and rapid agers Researchers at the University of Pittsburg Medical Center and the University of Pittsburgh School of Medicine have identified...

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Woman Performs Do-it-yourself Fecal Transplant to Relieve Symptoms of IBS, Gets Donor’s Acne

Clinical laboratory scientists and microbiologists could play a role in helping doctors explain to patients the potential dangers of do-it-yourself medical treatments Be careful what you wish for when you perform do-it-yourself (DIY) medical treatments. That’s the...

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Dutch Patient with Longest COVID-19 Case of 612 Days Had More than 50 SARS-CoV-2 Mutations Before He Died

Study of the 50 Omicron variants could lead to new approaches to clinical laboratory testing and medical treatments for long COVID Patients infected with SARS-CoV-2 can usually expect the COVID-19 illness to subside within a couple of weeks. However, one Dutch patient...

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Yale University’s Mobile Clinical Laboratory Provides Free Medical Tests to Underserved Communities in Connecticut

Clinical laboratories nationwide could follow Yale’s example and enact programs to bring much needed lab services to traditionally underserved communities Ever since the COVID-19 pandemic drove up demand for telehealth medical services, mobile clinical laboratories...

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Endocrine Society Releases New Guidelines Advising Physicians to Not Screen for Vitamin D, which Could Affect Test Referrals to Clinical Laboratories

New guidelines also advise people to limit their vitamin D supplementation to recommended daily doses Clinical laboratories may eventually receive fewer doctors’ orders for vitamin D testing thanks to new guidelines released by the Endocrine Society. The new Clinical...

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FDA Grants Marketing Authorization to First Ever AI-Powered SaMD Diagnostic Tool for Sepsis That Shares Patient’s Risk within 24 Hours and Works with EHRs

Infection control teams and clinical laboratory managers may want to look at this new product designed to improve the diagnosis and treatment of sepsis Accurate and fast diagnosis of sepsis for patients arriving in emergency departments is the goal of a new product...

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University College London Study Shows Direct-to-Consumer DNA Tests Not Reliable in Assessing Disease Risk

Regulatory agencies in UK and US have yet to address dangers inherent in customer misunderstanding of DTC medical laboratory genetic test results Direct-to-consumer (DTC) medical laboratory genetic tests are gaining popularity across the globe. But recent research out...

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Harvard and Google Scientists Studying Connectomics Create Massive Highly Detailed 3D Nanoscale Model of Human Neural Tissue

Ten year collaboration between Google and Harvard may lead to a deeper understanding of the brain and new clinical laboratory diagnostics With all our anatomic pathology and clinical laboratory science, we still do not know that much about the structure of the brain....

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Johns Hopkins Research Team Uses Machine Learning on DNA “Dark Matter” in Blood to Identify Cancer

Findings could lead to new biomarkers clinical laboratories would use for identifying cancer in patients and monitoring treatments As DNA “dark matter” (the DNA sequences between genes) continues to be studied, researchers are learning that so-called “junk DNA”...

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University of Ghent Belgium Research Team Finds Stool Transplants Improve Motor Symptoms in Early-stage Parkinson’s Disease Patients

Findings could lead to clinical laboratory tests that help physicians identify microbes lacking in the microbiomes of their Parkinson patients Microbiologists and clinical laboratory scientists know that gut microbiome can be involved in the development of Parkinson’s...

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Patient Rights Group Says Too Many Hospitals Are Not Complying with CMS Price Transparency Rules

Only about a third of the hospitals surveyed are in full compliance with giving public access to prices, the watchdog group contends, but the AHA disputes its methodology It’s been almost four years since the Centers for Medicare and Medicaid Services (CMS) enacted...

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Clinical Trial Shows New Laboratory Developed Blood Test 83% Effective at Detecting Colorectal Cancer

Accurate blood-based clinical laboratory testing for cancer promises to encourage more people to undergo early screening for deadly diseases One holy grail in diagnostics is to develop less-invasive specimen types when screening or testing for different cancers. This...

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New Zealand Blood Service Workers and Junior Doctors Hit the Picket Line Once Again to Fight against Pay Disparities and Poor Working Conditions

As before, the ongoing strikes continue to cause delays in critical clinical laboratory blood testing and surgical procedures After seven months of failed negotiations, New Zealand’s blood workers, clinical laboratory technicians, and medical scientists, are once...

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UK’s National Health Service Tests AI Tool That Can Spot Cancer in Mammograms Missed by Doctors

This AI platform has the potential to also reduce workload of radiologists, but also of anatomic pathologists and oncologists allowing them to be more productive When the UK’s National Health Service (NHS) recently tested an artificial intelligence (AI) platform’s...

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Ex-Theranos Founder and CEO Elizabeth Holmes Reduced Her Prison Sentence by Nearly Two Years

Good behavior in federal prison by the disgraced founder of the now-defunct clinical laboratory company earned her the reduction in her original sentence of 11 years Elizabeth Holmes, founder of failed clinical laboratory blood analysis company Theranos, continues to...

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University of Warwick Researchers Identity Blood Protein Biomarkers That Can Predict Dementia Onset Years in Advance

With further study, this research may provide clinical laboratories with a new proteomic biomarker for dementia screenings that identifies risk more than 10 years before symptoms appear Researchers at the University of Warwick in the UK and Fudan University in...

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University of Pittsburgh Pathologists Create World Tumor Registry to Assist Medical Professionals in the Identification and Diagnosis of Cancers

As the cancer registry expands it will increasing become more useful to anatomic pathologists, histopathologists, oncologists, and even clinical laboratories Oncologists, histopathologists, anatomic pathologists, and other cancer physicians now have a powerful new...

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NIH Scientists Develop New Clinical Laboratory Assay to Measure Effectiveness of ‘Good’ Cholesterol

Clinical studies show that new ‘cell-free’ test can predict cardiovascular disease risk better than standard HDL cholesterol test Researchers from the National Institutes of Health (NIH) have developed a diagnostic assay that measures how well high-density lipoprotein...

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Washington University School of Medicine Researchers Find Accelerated Aging May be Contributing to an Increase in Early-onset Cancers among Young People

More research into accelerated aging may lead to new clinical laboratory and anatomic pathology testing biomarkers for early-onset cancer Could accelerated aging be contributing to the rise in early-onset cancer rates among younger individuals? A recent study...

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