Discovery That Modern Humans Aren’t Especially Unique, Genetically Speaking, May Lead to Improved Precision Medicine Diagnostics and Therapeutics

Of interest to clinical pathologists is the finding that sequencing the genomes of Humans and Neanderthals revealed a link between severity of COVID-19 infections and Neanderthal DNA Genetic scientists from the University of California Santa Cruz have learned that just 7%—or less—of our DNA is unique to the human species, with the remainder of our genomes coming from other archaic species, such as Neanderthal and Denisovan. Why should this matter to pathologists and clinical laboratories?...

New Test Under Development That Detects Breast Cancer within One Hour with 100% Accuracy Has Potential to Help Pathologists Deliver More Value

Such a test, if proved safe and accurate for clinical use, could be a useful diagnostic tool for anatomic pathologists What would it mean to anatomic pathology if breast cancer could be diagnosed in an hour from a fine needle aspiration (FNA) rather than a core biopsy? A new test created by researchers affiliated with Massachusetts General Hospital in Boston may be just such a game changer. Especially in remote locations where clinical laboratory resources are in short supply. Regardless of...

Does Precision Oncology Offer Patients Superior Treatment Therapies? Anatomic Pathologists Will Be Interested to Learn Why Oncology Experts Disagree

Number of patients eligible for genome-driven oncology therapy is increasing, but the percentage who reportedly benefit from the therapy remains at less than 5% Advances in precision medicine in oncology (precision oncology) are fueling the need for clinical laboratory companion diagnostic tests that help physicians choose the best treatment protocols. In fact, this is a fast-growing area of clinical diagnostics for the nation’s anatomic pathologists. However, some experts in the field of...

Swiss Researchers Use New Mass Spectrometry Technique to Obtain Protein Data, Create Strategy That Could Lead to Clinical Laboratory Advances in Personalized Medicine

Researchers believe they have begun to crack open a ‘black box’ involving the genomes and diseases of individual patients Researchers in Switzerland are developing a new way to use mass spectrometry to explain why patients respond differently to specific therapies. The method potentially could become a useful tool for clinical laboratories that want to support the practice of precision medicine. It is also one more example of how mass spectrometry is being used by researchers to develop new...

Research Team at University of California Santa Barbara Achieves In Vivo Monitoring of Therapeutic Drugs with Technology That Pathologists Could Adapt for Clinical Diagnostic Purposes

Published study involved a demonstration of the MEDIC device’s ability to measure therapeutic drugs in animals, as well as human whole blood Researchers at the University of California Santa Barbara (UCSB) are making rapid progress in designing a biosensor that can measure therapeutic levels of a prescription drug in real time within the patient. This technology has interesting implications for anatomic pathology and clinical laboratory testing. The research team has developed a small...
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