Scientists Use Thousands of Genetic Markers to Develop Risk Scores for Six Common Diseases: Findings May Have Implications for Clinical Laboratories

Study demonstrates how precision medicine is advancing because of new insights from the use and interpretation of whole-genome sequencing As part of the Genomic Medicine at Veterans Affairs Study (GenoVA), researchers from Harvard Medical School, Veterans Affairs Boston Healthcare System, and Brigham and Women’s Hospital in Massachusetts used thousands of genetic markers to develop and validate polygenic risk scores (PRS) for six common illnesses. These findings may eventually provide clinical...

Canadian Scientists May Have Discovered Why Astronauts Suffer from ‘Space Anemia’

Study conducted on International Space Station found crew’s red blood cells were destroyed 54% faster in space than while on Earth Hemolysis in blood specimens is something that clinical laboratories deal with every day. Now researchers in Canada have determined that, while astronauts are in space, hemolysis is a causative factor in the condition known as “space anemia.” Hematologists whose clinical laboratories process a steady volume of complete blood count (CBC) tests to diagnosis anemia...

Researchers Find Health of Human Microbiome Greatly Influenced by Foods We Eat

One key finding of interest to clinical laboratory scientists is that this research study indicates that the human microbiome may more closely correlate with blood markers of metabolic disease than the genome of individuals In the search for more sensitive diagnostic biomarkers (meaning the ability to detect disease with smaller samples and smaller quantities of the target biomarker), an international team of researchers has teased out a finding that a panel of multiple biomarkers in the human...

Stanford University Study Traces Hospital-Acquired Bloodstream Infections to Patients’ Own Digestive Tract

New bioinformatic tool finds gut microbiota may be ‘potential reservoir of bloodstream pathogens’ suggesting patients’ own bodies can be source of infections Clinical laboratories in hospitals and health networks throughout the nation are collaborating in the priority effort to reduce deaths from sepsis and related blood infections. Now comes news that researchers at Stanford have identified an unexpected source of bloodstream infections. This finding may help medical laboratories contribute...

Researchers at Stanford University and Intel Develop Silicon Microarray Chip Capable of Producing Clinical Pathology Laboratory Test Results in Minutes

Pathologists and clinical laboratory managers take note—this peptide chip microarray may have a role in point-of-care testing At the heart of a new point-of-care technology is a prototype silicon chip that contains up to 9,000 peptides and allows real-time analysis in just minutes. Researchers say this technology can significantly reduce the time-to-answer when compared to existing clinical laboratory testing technologies. This new prototype silicon chip is an on silico peptide microarray. It...
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