News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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Stanford Study Shows How Pathologists May Eventually Use the Whole Human Genome for Diagnostic Purposes

Researchers use patient’s whole genome to predict his risk for 55 different health conditions


For pathologists, the day draws ever closer when they will use a patient’s whole genome sequence for diagnostic purposes. That’s the implication from research being done at the University of Stanford Medical School where scientists recently made a leap forward in advancing practical application of the human genome to patient care.

Stanford researchers recently announced that, for the first time, a healthy person’s complete DNA was sequenced, then used to create an easy-to-use, cumulative risk report. This study model could catapult patient genomic analysis into clinical laboratories even as it adds personalized medicine to the doctor’s black bag of diagnostic tools within the decade. The Stanford study team reported these findings in a recent issue of Lancet.

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Boutique Medicine Venture Generates Marketing Intelligence for Procter & Gamble

Consumer products giant acquires 100% ownership of concierge medicine company

Clinical laboratories and pathology groups may soon be serving physician practices owned by Procter & Gamble (P&G) (NYSE:PG). That’s because the consumer products giant now owns 100% of MDVIP, a nationwide concierge practice of 350 doctors in 28 states.

The deal is noteworthy because it further expands Procter & Gamble’s presence in healthcare. In 2006, P&G invested $325 million in a joint venture with Inverness Medical (NYSE:IMA). The joint venture announced its intention to develop and market diagnostic test kits for use by consumers that can be sold in retail outlets. At the time, The Dark Report wrote that, “P&G’s interest in consumer self testing is based on its belief that consumer demand for health services and healthcare products will soar in the coming decades.”  (See The Dark Report, June 4, 2007, “ Inverness Buys Biosite, Has New Venture with P&G” )

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New Clinical Laboratory DNA Test Identifies Sepsis Patients in Just 18 Hours

Researchers say Mobidiag’s microarray-based diagnostic test technology looks promising

There’s a new DNA-based microarray platform that could speed identification of blood-borne pathogens. By allowing clinical laboratories to deliver test results in just 18 hours, use of this new microarray could improve early detection and management of sepsis patients.

In a study headed by Päivi Tissari, M.D., of the Division of Clinical Microbiology, Helsinki University Hospital Laboratory in Finland, the Prove-it sepsis assay, manufactured by Helsinki-based Mobidiag, demonstrated 94.7% clinical sensitivity, 98.8% specificity, along with 100% sensitivity and specificity for methicillin-resistant Staphylococcus aureus bacteremia. The conventional process of growing a culture—the medical laboratory’s gold standard—typically takes between one to three days to become positive and two more days to identify the bacteria and their antibiotic sensitivity patterns. Mobidiag’s Prove-it sepsis assay returns results in only 18 hours.

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New Technology Captures Tumor Cells from the Bloodstream

Nano-technology Breakthrough May Prevent Cancers from Metastasizing

With the goal of removing tumor cells from the bloodstream, a biomedical engineering team at the University of Arkansas for Medical Sciences (UAMS) in Little Rock has discovered a non-invasive way to identify cancer and to capture tumor cells in the bloodstream. This landmark discovery, could dramatically improve early cancer diagnosis and prevent deadly metastasis. It could also provide a framework for a new type of diagnostic test that could detect metastatic cancer from a blood sample.

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Nation’s List of Top Ten Largest Healthcare Systems Include Some Surprises

Rankings based on annual revenue and the Veterans’ Administration tops the list

When Dark Daily recently published a list of the Top Ten Largest Medical Groups in the United States, not only was it a popular topic, but many readers asked us to present a similar list for healthcare systems. Dark Daily is glad to oblige and presents below a list of the Top Ten Largest Healthcare Systems in the United States, ranked on annual revenue.

This ranking of the Top Ten Biggest Healthcare Systems includes government healthcare systems, not-for-profit healthcare systems, and for-profit healthcare systems. As you will see, the U.S. Department of Veteran Affairs holds down the number one position, with annual revenue of $40.7 billion. Coming in second on this ranking is HCA, Inc., with annual revenue of $28.4 billion. Of the ten largest healthcare systems, three are owned by Catholic organizations and three are for-profit hospital corporations.

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