University of Michigan Researchers Use “Labyrinth” Chip Design in Clinical Trial to Capture Circulating Tumor Cells of Different Cancer Types

Research goal was to isolate circulating tumor cells in venipuncture samples with improved purity compared to standard spiral chips Many research teams are pursuing the goal of creating assays that detect circulating tumor cells (CTCs) that would allow earlier and more accurate diagnosis of cancer. Now comes news of a unique technology developed at the University of Michigan (U-M) Ann Arbor that showed promised in an early study. The method of using CTCs to diagnose cancer in patients, while...

Digital PCR Poised to Give Traditional Real-Time PCR a Run for Its Money in Gene Sequencing and Development of New Medical Laboratory Tests

Adoption of digital PCR is slow at this time, but pathologists may want to track how researchers use this technology in the new clinical laboratory assays they use Molecular pathologists will be interested to learn that there is a new contender in the polymerase chain reaction (PCR) arena. It is digital PCR, and it has specific advantages over traditional real-time PCR methods. For example, digital PCR can target specific DNA sequences in just one molecule of DNA. This new tool allows...
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