News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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Sound Wave Acoustic Tweezers Locate and Isolate Circulating Tumor Cells in Liquid Biopsies; Could Lead to Less Invasive Cancer Diagnostics and Treatments

Pathologists will be interested to learn that this latest version of the acoustic tweezer device requires about five hours to identify the CTCs in a sample of blood

Medical laboratory leaders and pathologists are well aware that circulating tumor cells (CTCs) released by primary tumors into the bloodstream are fragile and easily damaged. Many studies have sought to find ways to separate CTCs from surrounding cells. Such a process could then be used as an early-detection biomarker to detect cancer from a sample of blood.

One team of researchers believe it has a way to accomplish this. These researchers are using sound waves to gently detect and isolate CTCs in blood samples. In turn, this could make it possible to diagnose cancer using “liquid biopsies” as opposed to invasive conventional biopsies.

Researchers from Carnegie Mellon University (CMU) in collaboration with researchers from the Massachusetts Institute of Technology (MIT) and Pennsylvania State University (Penn State) have developed a method for using acoustic tweezers and sound waves to separate blood-borne cancer cells from white blood cells. The research team believes this new device could one day replace invasive biopsies, according to a CMU article. (more…)

New Clinical Laboratory Test Exposes Cancer Cells with Ultra Violet Light: Improves Accuracy of Current Cancer Assays, Say Researchers

New technology accurately distinguishes between cancerous cells and healthy cells. Will it give pathologists a “universal” assay for cancer diagnosis?

In England, a university team has developed a new technology for detecting circulating cancer cells in blood. Their method uses ultraviolet light and the results are so promising that efforts are now underway to develop this method into a clinical laboratory test.

That is why pathologists and medical laboratory professionals may soon have a new tool in their arsenal: one that significantly aids physicians and medical laboratories in the diagnosis of cancer. (more…)

Collaboration of Caltech Engineers and LeukoDX Produces Prototype Point-of-Care Device That Counts White Blood Cells in Minutes in the Patient’s Home

The science behind the device is an innovative detection assay of dyes that stain leukocytes so they will fluoresce and enable differentiation of white blood cell subtypes 

Over the last couple of years, medical laboratory technology developers have brought a number of FDA-approved point-of-care (POCT) and home self-tests to market.

These medical tests run the full spectrum. They include tests to detect HIV, malaria, pregnancy or male fertility, drug use or Hepatitis C. There are tests to monitor liver function, glucose in diabetics, cholesterol; and provide needle-free CBCs and genetic tests. (more…)