Feb 26, 2014 | Digital Pathology, Instruments & Equipment, Laboratory Management and Operations, Laboratory News, Laboratory Operations, Laboratory Pathology
Researchers at Penn State identified 160,000 ‘transcription initiation machines’ throughout the human genome
DNA “dark matter” may have something in common with comedian Rodney Dangerfield, who liked to say, “I don’t get no respect!” As many pathologists know, for years the human exome that has been the focus of most research. This is the 1% of the human genome that contains the genes that produce proteins and do other useful functions.
Meanwhile, the remaining 99% of the human genome—sometimes called “junk DNA” and generally known as dark matter—got relatively little attention from researchers. But that is changing. At Pennsylvania State University, a research team has discovered that coding and noncoding RNA, or genomic dark matter, originates at the same types of locations along the human genome.
(more…)
Aug 12, 2013 | Coding, Billing, and Collections, Laboratory Instruments & Laboratory Equipment, Laboratory Management and Operations, Laboratory News, Laboratory Pathology
Technology breakthrough might eventually be used by pathologists to help diagnose disease using in vivo diagnostic testing methods
Researchers at Stanford University are another step closer to understanding how to make DNA and RNA function like computer chips fabricated from silicon. Their work could eventually form the basis for new types of diagnostic services that could be offered by clinical laboratories and anatomic pathology groups.
Stanford Bioengineers Develop Final Component for Biological Computer
Bioengineers at Stanford University have engineered a genetic circuit to behave like a transistor in individual living cells, according to a story published by the San Jose Mercury News. The achievement represents the final component of a simple biological computer that functions within individual cells of the body.
These biological computers could be used in several ways. They could screen for cancer, or be used to detect the presence of toxic chemicals. Some experts believe they could be used to guard against disease, reported the Mercury News. (more…)