News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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University Engineering Student Invents Cheap Point-of-Care Fluorescence Microscope

Pathologists take note: device created with off-the-shelf parts rivals accuracy of $40,000 model!


Pathologists know the engineering complexity and expense of today’s state-of-the-art fluorescence microscopes. Now comes news that a Rice University biomedical engineering student has developed a portable, battery-operated bright field and fluorescence microscope that rivals the performance of reference-standard devices retailing for as much as $40,000!

The student, Andrew Miller, developed the 2.5-pound microscope as part of his senior project in 2009, working with faculty in Rice 360˚: Institute for Global Health Technologies. Miller’s project was intended to develop diagnostic tools for underdeveloped countries. He calls his instrument the “Global Focus microscope,” Remarkably, he built it using off-the-shelf parts that cost just $240. The light required to power the 1,000-times magnification microscope comes from a top-mounted LED flashlight.

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Molecular Diagnostics Laboratory in a Suitcase Travels to Farms to Test Livestock

New molecular point-of-care testing systems already being tested in several African countries

Pathologists will be interested to learn that sophisticated point-of-care molecular diagnostics testing is now being done on livestock in farms. This is a giant leap forward for point-of-care testing, as there are now commercially available suitcase-sized devices used to perform molecular diagnostic tests for avian flu in livestock. These molecular testing systems are undergoing trials in Africa, primarily Sudan and Kenya.

Development of the devices was partially funded through a joint project of the International Atomic Energy Agency (IAEA) and the Food and Agriculture Organization (FAO). The organizations are concerned about trans-boundary animal diseases that, like the avian flu, can cross from one species to another. These agencies funded research to develop molecular diagnostic methods to rapidly identify such diseases. The avian flu test is the first to make use of this new molecular technology.

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Hematology on a Chip: University of Southampton Develops POC Blood Analysis

In conjunction with Phillips Research, a team from the University of Southampton is looking to revolutionize blood analysis

Point-of-care blood cell analysis in doctor’s offices could soon be much faster and more convenient. In conjunction with Philips Research, a team of researchers at England’s University of Southampton is developing a miniaturized cell analysis device with the  goal of eventually delivering a low cost, high speed, and inexpensive system to perform CBCs (complete blood counts) in point-of-care settings.

The team recently developed a microfluidic single-cell impedance cytometer with the ability to execute a white cell differential count. A microchip within the cytometer uses microfluidics to assess various cells in the blood. The electrical properties of the blood cells are assessed while the blood actually flows through the chip. The measurements are used to determine and count the different types of cells and would allow physicians to diagnose several different types of diseases. The device can identify three types of white blood cells (T-lymphocytes, monocytes and neutrophils) quicker and more inexpensively than current systems.

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New Point-of-Care Test and Monitor Devices Used by Chronically Ill Patients at Home

More sophistication and performance in new POCT and monitoring systems for home use

Efforts to increase patient home self-testing and monitoring continue to pay off. Two new products for point-of-care (POC) health tests and patient home monitoring recently entered the marketplace. Both systems are devices that enable healthcare professionals to remotely monitor patients with chronic illnesses.

Separately, UK-based The Jaltek Group and Sweden-based Ericsson each introduced wireless monitoring systems worn by patients at home or in healthcare facilities. These systems improve patients’ quality of life by continuously monitoring their vital signs while allowing free movement. These devices also avoid the need for frequent trips to the doctor and may lower health care costs.

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Cleveland Clinic and Microsoft Team up to Use Point-of-Care Testing in EMR Network

New care delivery model might emerge from collaboration between two partners

Guess which famous health provider is partnering with Microsoft (NASDAQ:MSFT) to encourage patients using home self-testing devices to regularly upload those data into an electronic medical record? It’s the Cleveland Clinic Health System. This project may point to a disruptive new model for laboratory testing.

It’s a pioneering arrangement. Microsoft’s HealthVault is interfaced with the eCleveland Clinic MyChart patient portal to create an interactive feature that collects data on from in-home medical devices used by patients with chronic conditions. The pilot project includes 460 patients with diabetes, congestive heart failure and hypertension. These patients use home blood pressure monitors, glucometers, and weight scales which are linked to the HealthVault platform personal health record (PHR) system.
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