News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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Point-of-Care Testing Conference Draws Big Crowd in Toronto to Learn about New Diagnostic Technologies, Improving Test Quality, and Accuracy

Ontario’s Institute for Quality Management in Healthcare convened the conference to help advance the effective use of point-of-care-testing by clinical laboratories

DATELINE—Toronto, Ontario, Canada: Interest in point-of-care testing (POCT) is strong in Canada. Evidence of that comes from a crowd of more than 240 clinical laboratory professionals and in vitro diagnostics (IVD) vendors who attended the “The Future of Point-of-Care Testing—A Healthy Debate!” conference here last week.

The meeting was organized by the Institute for Quality Management in Healthcare (IQMH). Based in Toronto, IQMH provides the ISO 15189 accreditation services used by medical laboratories in Ontario to meet the province’s lab licensure requirements. IQMH also handles lab accreditation for several other provinces.

“Because of the ever-greater use of POCT in clinical settings throughout Canada, IQMH has organized this conference regularly in recent years,” stated pathologist Gregory J. Flynn, MD, CEO of IQMH. “It is one of the few clinical laboratory programs that brings together experts and users to discuss issues of quality, clinical relevance, and the challenges in using point-of-care testing in support of patient care.” (more…)

Researchers at University of Rhode Island Unveil Lab-on-Paper Test Capable of Multireagent Diagnostics: Could Enable ‘Diagnostics Without the Lab’ say Developers

New diagnostic capabilities could enable clinical laboratories to obtain multiple outcomes on single fluidic strip tests

Researchers at the University of Rhode Island (URI) have developed a paper-based microfluidic valve technology that some claim may revolutionize existing lateral-flow tests. There is the potential for this innovation to eventually enable pathology groups and medical laboratories to conduct a wide variety of complex medical diagnostics on single fluidic test strips, such as those used to diagnose pregnancy and strep throat, according to a university statement.

Testing Multiple Biomarkers Using a Single Test Strip

Fluidic test strips commonly in use today are generally capable of rendering only one result. However, by combining their new paper-based valve platform with standards strip tests, the URI research team has produced strip tests capable of answering more challenging medical questions.

The evolution of the new technology, dubbed “Lab-on-Paper,” follows the development of the team’s earlier “lab-on-a-chip” device, which the researchers began developing back in 2005. (more…)

Sleek ‘Lab in a Needle’ Is an All-in-One Device That Detects Liver Toxicity in Minutes during a Study, Showing Potential to Supplant Some Medical Laboratory Tests

Researchers’ prototype uses lab-on-a-chip technology and seems to do it all, from collection and analysis to results in minutes and in the palm of your hand

Here’s a diagnostic workhorse that can also easily slip inside the pocket of a doctor’s white coat. The slim device, created and reported by researchers, integrates a clinical laboratory’s workflow from collecting samples to analyzing them and reporting results in minutes.

The device is dubbed “lab in a needle” by researchers at Houston Methodist and their collaborators at Singapore’s Nanyang Technological University (NTU) and the Singapore Institute of Manufacturing Technology (SIMTech). The recently announced study focused on liver toxicity. But the research team says in a news statement that their medical laboratory-in-a-needle has potential to diagnose and monitor therapies for many health conditions in settings well beyond the medical laboratory and hospital.

For clinical laboratory leaders and pathologists, the prototype can be seen as another step forward in efforts to develop more sophisticated point-of-care testing (POCT) that incorporate miniature lab-on-a-chip (LOC) technologies. Mass production could bring the tiny mobile lab’s capabilities to remote and rural communities where low cost and ease of use are essential. (more…)

Engineers at Michigan Technological University Create Pocket-Sized, Multi-Test Medical Lab-on-a Chip Using Computer-Aided Design Technology

Unique pocket-sized lab could provide doctors immediate test results, reduce costs for budget-strapped clinical laboratories, and serve as a lab-testing tool for doctors working in remote areas

For almost two decades, developers have touted the potential of lab-on-a-chip technology to play a greater role in clinical laboratory testing. Now the latest twist on this technology story is that computer engineers are using the power of computer-aided design (CAD) to develop innovative lab-on-a-chip (LOC) designs.

This innovative work was created by two computer engineers from Michigan Technological University (MTU). Working together, T. Shiyan Hu, Ph.D., Associate Professor of Electrical and Computer Engineering at MTU, and doctorate student Chen Liao have created two computer-generated configurations for routing a droplet of blood or other bodily specimen through multiple LOC channels. Their invention would facilitate running dozens of different diagnostic tests, from HIV to diabetes, on a single LOC. (more…)

Multi-national Gathering of Clinical Laboratory Professionals Assesses Benefits and Problems with Point-of Care Testing in Toronto this Week

Pathologists and medical laboratory professionals heard speakers from Sweden, Australia, New Zealand, and Canada discuss the latest developments in POCT

TORONTO, ONTARIO—Spirited discussion always results when pathologists and clinical laboratory professionals discuss point-of-care testing (POCT). That was certainly true during a special POCT workshop that took place here this week.

Attendees came from as far away as Sweden, Australia, and New Zealand to attend “Point-of-Care Testing: Today and Tomorrow.” The conference was produced by the Toronto-based Institute for Quality Management in Healthcare (IQMH).

Point-of-Care Testing Has an Essential Role in Patient Care

As most medical laboratory scientists know, POCT can be both a blessing and a curse. When used properly, POCT plays an essential role in patient care and can guide physicians in ways that improve outcomes. However, problems associated with the ongoing management and performance of an organization’s POCT program regularly frustrates laboratory scientists tasked with oversight of POCT. (more…)

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