Mathematical Modeling of Systems Pharmacogenetics by Researchers at Penn State May Create New Opportunities for Clinical Pathology Laboratories

Goal is to apply differential equations with pharmacogenomics to better predict a patient’s response to prescription drugs, a development that could create role for pathologists to help clinicians interpret the data from such medical lab testing

New approaches to mathematical modeling are poised to transform pharmaceutical drug research and development—and create new opportunities in clinical laboratory testing down the road. U.S. and Chinese scientists have developed statistical models that more accurately simulate a drug’s reaction in a patient.

Using differential equations, these researchers seek to integrate mathematical modeling of drug reactions into pharmacogenomics. Their goal is to better predict interpersonal differences in drug response based on genetic information. This will help clinicians to develop a strategy for personalized drug delivery. (more…)