Penn State University College of Medicine Pilot Study Finds MicroRNA in Saliva Can Be Used in Diagnosis and Treatment of Concussions in Children

Identifying patients who will likely develop prolonged concussion symptoms could lead to new clinical laboratory tests and personalized medicine treatments Researchers are homing in on a new diagnostic assay for concussion that could potentially generate significant numbers of test referrals to the nation’s clinical laboratories. This innovative work is targeting how concussions are diagnosed and treated. Each year, thousands of children receive sports-related injuries, including concussions....

Children’s Study Determines MicroRNA in Saliva Can Accurately Diagnose Acute and Prolonged Concussion Symptoms; Could Lead to New Medical Laboratory Tests and Point-of-Care Diagnostics

Research published in JAMA Pediatrics reports that non-invasive salivary microRNA testing identifies prolonged concussion symptoms with 85% accuracy Sports-related concussions are always tragic, but doubly so when they involve child athletes. Quick diagnoses and treatments are critical to prevent permanent brain injury. But doctors are often hampered by the pace at which traditional medical imaging modalities and clinical laboratory diagnostic technologies provide crucial feedback. Now,...

Mathematical Modeling of Systems Pharmacogenetics by Researchers at Penn State May Create New Opportunities for Clinical Pathology Laboratories

Goal is to apply differential equations with pharmacogenomics to better predict a patient’s response to prescription drugs, a development that could create role for pathologists to help clinicians interpret the data from such medical lab testing New approaches to mathematical modeling are poised to transform pharmaceutical drug research and development—and create new opportunities in clinical laboratory testing down the road. U.S. and Chinese scientists have developed statistical models that...
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