Nov 22, 2010 | Laboratory News, Laboratory Pathology
Clinical laboratory-on-a-chip would cost under £1 and allow young people to test themselves for sexually-transmitted diseases
Some wags call a new diagnostic testing concept the “pee in the cell phone” pathology lab test. The humor is directed at cell phone-based medical laboratory tests under development in the hopes that this confidential and private diagnostic test method will encourage more young people to undergo testing for sexually-transmitted diseases (STDs).
Newspapers in the United Kingdom are reporting on a research project—funded in part by the government—to develop STD tests that can be run on a USB-size chip that is inserted into a smart phone or a personal computer.
This project is a response to the significant rise in sexually transmitted infections (STIs) among young people. In the United Kingdom, the rate of new infections for herpes, chlamydia and gonorrhea are rising to record levels.
Clinical Laboratory Test on a Cell Phone or Personal Computer
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Dec 4, 2009 | Laboratory News, Laboratory Pathology
Nano-technology Breakthrough May Prevent Cancers from Metastasizing
With the goal of removing tumor cells from the bloodstream, a biomedical engineering team at the University of Arkansas for Medical Sciences (UAMS) in Little Rock has discovered a non-invasive way to identify cancer and to capture tumor cells in the bloodstream. This landmark discovery, could dramatically improve early cancer diagnosis and prevent deadly metastasis. It could also provide a framework for a new type of diagnostic test that could detect metastatic cancer from a blood sample.
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Oct 19, 2009 | Digital Pathology, Laboratory Pathology, Management & Operations
In conjunction with Phillips Research, a team from the University of Southampton is looking to revolutionize blood analysis
Point-of-care blood cell analysis in doctor’s offices could soon be much faster and more convenient. In conjunction with Philips Research, a team of researchers at England’s University of Southampton is developing a miniaturized cell analysis device with the goal of eventually delivering a low cost, high speed, and inexpensive system to perform CBCs (complete blood counts) in point-of-care settings.
The team recently developed a microfluidic single-cell impedance cytometer with the ability to execute a white cell differential count. A microchip within the cytometer uses microfluidics to assess various cells in the blood. The electrical properties of the blood cells are assessed while the blood actually flows through the chip. The measurements are used to determine and count the different types of cells and would allow physicians to diagnose several different types of diseases. The device can identify three types of white blood cells (T-lymphocytes, monocytes and neutrophils) quicker and more inexpensively than current systems.
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Apr 10, 2009 | Digital Pathology, Instruments & Equipment, Laboratory Instruments & Laboratory Equipment, Laboratory News, Laboratory Operations, Laboratory Pathology
New diagnostic and treatment approach will require close interaction with Pathologists
There’s a novel diagnostic device designed to detect sepsis that also has to potential to engage the pathologist as part of the bedside care team. It is also an example of how nanotechnology and magnetism are being combined in ways that may support in vivo diagnosis and treatment.
Created by a research scientist at Children’s Hospital Boston, this new device uses magnetism to quickly pull disease pathogens out of infected blood. Experts predict it could become the first line of defense for sepsis, a disease which kills about 200,000 Americans each year.
The system works by drawing the patient’s blood and adding tiny magnetic beads, pre-coated with antibodies against specific pathogens, such as Candida albicans. The blood is run through a microfluidic system in which two liquid flow streams run side by side without mixing. One channel contains blood and the other contains a saline-based collection fluid. The beads bind to the pathogens. A magnet then pulls them, along with the pathogens, into the collection fluid. The collection fluid is ultimately discarded, and the cleansed blood reintroduced into the patient.
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