News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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Pathologists at South Carolina Hospital Are Preparing to Use Next Generation Gene Sequencing for Cancer Patients

Strategic collaboration promises leap forward in personalized medicine that could be game-changing for medical laboratories

One early effort to apply next generation gene sequencing to cancer diagnostics and therapeutics is a collaboration that involves Greenville Hospital System University Medical Center (GHS) in Greenville, South Carolina, and Lab21, Inc., a British company. GHS wants to use next gene sequencing as an integral part of the evaluation of every cancer patient cared for in the GHS system.

The partnership between GHS and Lab21 provides evidence for pathologists and clinical laboratories that first mover hospitals and health systems are now taking steps to incorporate next generation gene sequencing (NGS) into their cancer care protocols. Forward-looking pathology groups are already taking steps to expand their capabilities to perform and interpret genetic tests. (more…)

Pathology Labs Might Benefit from $1 Million Challenge to Sequence the Genome of a Single Cancer Cell

Goal is to produce accurate sequence of one human cancer cell; could lead to new cancer tests

Pathologists and clinical laboratory managers will find the latest “prize” for a genetic breakthrough to have direct relevance to molecular diagnostics. One million dollars will go to the first person who sequences an entire cancer cell genome, including all of the RNA, using a specific whole human genome sequencer made by Carlsbad, California-based Life Technologies (NASDAQ: LIFE).

This is the fourth of seven challenges being put out to the public at large. It is part of the global biotechnology company’s crowdsourcing initiative, dubbed the “Life Grand Challenges Contest.” Life Technologies first announced the contest in December of 2010, and since then, has posed three earlier challenges, each one also paying $1 million upon completion and verification.

Is Whole-genome Sequencing Reaching a Tipping Point for Clinical Pathology Laboratories?

High-Density Sequencing Chips Will Soon Be Able To Sequence Five Million SNPs

Rapid gene sequencing is catching the interest of progressive anatomic pathologists. These medical laboratory professionals are interested in using rapid gene sequencing technology to allow them to study tens and hundreds of genes on a patient specimen.

The technologies used in rapid gene sequencing are being developed and improved by a handful of biotech companies who are racing each other be first to deliver systems to the marketplace that can sequence whole human genomes at a cost of $1,000 or less. Some innovative medical laboratories are beginning to acquire these sequencing systems and explore how they might be used for clinical pathology laboratory testing. (more…)