News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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Comparison of In Vitro Diagnostic Industry’s Top Five Trends for 2015 and 2016 Reveals Rapid Technology Advances Intended to Give Clinical Laboratories New Diagnostic Tools

Of the five trends described in a report published by Kalorama, only two made the list for both years: Consolidation within the IVD industry and growth in molecular point of care

What a difference one year can make in the most significant trends influencing the in vitro diagnostics (IVD) industry, which also influences clinical laboratories, the largest customers of IVD manufacturers. These insights come from comparing the top five IVD trends for 2016 as identified by Kalorama Information from its top five IVD trends that it says dominated during 2015.

Kalorama is a division of MarketResearch.com, a company that publishes market research in the life sciences. In a report titled, “Five IVD Market Trends to Watch for in 2016,” it published its picks for the top five trends in IVD testing for 2016. The five most prominent trends recognized by the healthcare research marketer are as follows: (more…)

Researchers at University of Rhode Island Unveil Lab-on-Paper Test Capable of Multireagent Diagnostics: Could Enable ‘Diagnostics Without the Lab’ say Developers

New diagnostic capabilities could enable clinical laboratories to obtain multiple outcomes on single fluidic strip tests

Researchers at the University of Rhode Island (URI) have developed a paper-based microfluidic valve technology that some claim may revolutionize existing lateral-flow tests. There is the potential for this innovation to eventually enable pathology groups and medical laboratories to conduct a wide variety of complex medical diagnostics on single fluidic test strips, such as those used to diagnose pregnancy and strep throat, according to a university statement.

Testing Multiple Biomarkers Using a Single Test Strip

Fluidic test strips commonly in use today are generally capable of rendering only one result. However, by combining their new paper-based valve platform with standards strip tests, the URI research team has produced strip tests capable of answering more challenging medical questions.

The evolution of the new technology, dubbed “Lab-on-Paper,” follows the development of the team’s earlier “lab-on-a-chip” device, which the researchers began developing back in 2005. (more…)

Researchers at Howard Hughes Medical Institute Develop Blood Test That Reveals a Patient’s Viral History; Could Reduce Unnecessary Clinical Laboratory Testing

The VirScan test gives doctors insight into a patient’s lifetime exposure to viruses and thus may be developed into a useful medical laboratory test

Scientists and pathologists are learning that blood is like a time capsule, holding precious information about exposure to viruses over the years—chickenpox at five, mononucleosis at 18, flu at 40. You get the idea.

Now, researchers at Howard Hughes Medical Institute (HHMI)  have found a way to tap that entire data stream, so to speak. An inexpensive blood test, they say, reveals every virus that has passed through the body over time.

New Discoveries Could Lead to a Useful Clinical Laboratory Test

The testing method, called VirScan by researchers, is an efficient alternative to current medical laboratory tests that test for specific viruses one at a time, according to an HHMI news statement about the new technology. (more…)

Smartphone “Dongle” Achieves Capabilities of Big Clinical Laboratory Analyzers: Diagnoses Three Diseases at Once from Single Drop of Blood

This breakthrough in technology miniaturization holds great promise for improving public health, but portends a disruptive future ahead for the medical labs 

Is the medical laboratory industry ready for a handheld device that can do immunoassay testing without requiring any stored energy? The secret of this device, already undergoing field trials in Rwanda, is that it uses a smartphone accessory, or “dongle,” to capture and transmit the results of the lab tests.

This innovative smartphone device accurately diagnoses HIV and syphilis with a finger prick of blood and displays the results on the smartphone screen within 15 minutes, according to a Columbia Engineering News Service report.

An Ideal Device for Field Work in Resource Poor Areas

It’s mobile and inexpensive, making it an ideal diagnostic tool for use in poor, remote regions of the world. According to World Health Organization (WHO) statistics, the highest percentages of all sexually transmitted disease (STD) cases occur in developing and underdeveloped nations. (more…)

New Biosensing Film Can Diagnose Both Viral and Bacterial Infections Cheaply and Without the Need for Traditional Clinical Pathology Laboratory Tests

Researchers at Florida Atlantic University believe this technology could also be used to detect bacteria in food and water and to follow patients’ progress after leaving acute or outpatient care

New technology could shift the paradigm in infectious disease testing by clinical laboratories, while also giving hospitals a faster way to identify hospital-acquired infections (HAIs) and monitor patients for infections post-discharge. The diagnostic technology is built into a special “biosensing film” made of cellulose paper and a flexible polymer.

Researchers at Florida Atlantic University (FAU) developed the biosensing film. They say it can detect and discern HIV, Staphylococcus aureus, E-coli and other bacteria in blood, plasma, and saliva. The test is inexpensive, disposable, and portable. Best of all (at least for developing countries, remote locations, and places that have few resources), it requires no expensive infrastructure or a clinical laboratory.

And yes, the biosensing film is designed to work in tandem with a smartphone app. But in this case, the mobile app is only part of the story. The real genius is the piece of lightweight, flexible, “electronic paper” or “biosensing film” used with the app. The film acts as a platform that detects infections, both viral and bacterial.

The story of this inventive biosensing film is detailed in a Scientific Reports article in the March 5, 2015, edition of Nature. (more…)

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