Expanded Knowledge about Human Metabolome Expected to Fuel Development of New Therapeutic Drugs and Medical Laboratory Tests
Pathologists and clinical laboratory professionals can expect to see new molecular test development as researchers develop new biomarkers in the wake of expanded knowledge of the genome-metabolome-diseasome correlates
One field of science that bears great potential for use in diagnostics and medical laboratory testing involves the human metabolome. Researchers are gaining more understanding of the genetic underpinnings of complex disease and drug response through metabolic pathways.
For example, scientists at the Wellcome Trust Sanger Institute (WTSI) in the United Kingdom have linked 145 genetic regions with more than 400 molecules involved in metabolism in human blood, a story in Genetic Engineering News recently reported. The resulting atlas of associations will enable identification of genes that could be targeted in the development of drugs and clinical laboratory test. (more…)
