News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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University of Texas Researchers Develop New Techniques in Genetic Testing to Improve Clinical Laboratory Results through RNA

Innovative technological advances could potentially provide clinical laboratories, pathology groups, and medical researchers with improved methodologies for designing, performing, and analyzing lab tests that use genetic information

Researchers at the University of Texas at Austin (UT Austin) have developed an innovative new enzyme that promises to improve the methods and tools used by pathology groups and clinical laboratories when conducting genetic testing.

The enzyme enables the reproduction of large quantities of Ribonucleic acid (RNA) to be accurately duplicated. It also can perform reverse transcription and scrutinize itself while copying genetic information, which will enable both researchers and clinical laboratories to improve the accuracy of gene sequencing where RNA is involved.

The team published their findings in Science, the academic journal of The American Association for the Advancement of Science (AAAS) and filed for a provisional patent for the new sequence of the discovered enzyme. (more…)

New DNA Analysis Laboratory from Bento Bioworks Enables Anyone to Perform DNA Testing, Whether at Home or in Clinical Pathology Laboratories

Blood genotyping is one type of DNA test this miniature lab can perform as entrepreneurs work to take DNA testing out of medical laboratories and into other settings

It had to happen! There’s now a product designed to allow individuals to perform “do-it-yourself” DNA testing. Pathologists and clinical laboratory managers will be interested to learn that—for less than $800—they can acquire their own home set-up, which includes a PCR thermocycler, a centrifuge, a gel electrophoresis box, and a power supply with blue LED transillumination.

This new, compact, deoxyribonucleic acid (DNA) analysis product was developed to give individuals who want to work with DNA a fun and easy way to explore their genetic make-up.

It was developed by Bento Bioworks, a company based in London, England, and is described as a do-it-yourself DNA analysis kit called Bento Lab. The device is about the size of a laptop computer and may be used anywhere to conduct a variety of DNA experiments.

Bento Lab allows people to conduct simple DNA tests from samples obtained from saliva or hair follicles. Animal tissue, food, and drink samples may also be evaluated with the unit.

To perform an experiment, the user simply places a sample into a centrifuge located in the middle of the device. Bento Lab then extracts the DNA for analysis and a thermocycler targets a specific portion of the DNA and copies it. A gel unit then portrays the DNA to enable the user to interpret the results. (more…)

New Insights into Genetic Mechanisms Common to Humans and Simpler Species May Form the Basis for New Diagnostic Tests Performed by Clinical Pathology Laboratories

Scientists participating in the modENCORE study have the goal of understanding the causes of hereditary genetic diseases in humans

New discoveries about the interaction of genes and transcription factors in creating different types of RNA will be of interest to pathologists and clinical chemists performing genetic tests and molecular diagnostic assays in their medical laboratories.

The goal of this research is to better understand hereditary genetic disease in humans. The new knowledge is based on studies of the common fruit fly, or Drosophila melanogaster (D. Melanogaster), and to a lesser extent a tiny worm Caenorhabditis elegans (C. elegans). Both have been used as research models to study the human condition.

Research Could Give Pathologists New Diagnostic Tools (more…)

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