Personalized Medicine Experts Call on Pathology Profession to Create a New Breed of Pathologist

‘National Agenda’ seeks to marshal efforts to sharpen the clinical impact of pathology in the genomics era

Pathologists are being urged to seize the high ground as the unfolding revolutions in genomics and bioinformatics create unprecedented capabilities to more accurately diagnose patients and guide the selection of appropriate therapies.

Two experts in these fields have come together to issue a call to action for the pathology profession, stating that pathologists need to be prepared for the sequencing revolution. “Revolution is not too strong a word; this is not incremental change,” declared Dennis P. Wall, Ph.D. and Peter J. Tonellato, Ph.D., in a recent story published in The Scientist. “The use of whole-genome analysis (WGA) can, should, and will replace many current standard pathology practices of diagnosis and prognosis on which proper therapy and disease management rely,” the co-authors asserted.

Wall is an associate professor and director of Computational Biology at Harvard Medical School (HMS). Tonellato is a professor and director of the Laboratory for Personalized Medicine at HMS. (more…)