Harvard Researchers Develop Technology That ‘Turbocharges’ the Standard Medical Laboratory Microscope in Useful Ways
Breakthrough method could provide pathologists with a less expensive alternative to high-priced super-resolution microscopes or often-imprecise microscopy software
Intriguing new research has the potential to “turbocharge” the standard medical laboratory microscope in ways that create a “super-vision” capability. This would give pathologists and medical researchers an inexpensive alternative to high-priced super-resolution microscopes or often-imprecise microscopy software.
Seeking a new method for counting molecules in complexes, researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University paired their DNA-powered super-resolution microscopy platform—DNA-PAINT and Exchange-PAINT—with a new procedure called quantitative points accumulation in nanoscale topography—or qPAINT. This new analytic tool can “count different molecular species in biological samples with high accuracy and precision,” noted a Wyss Institute press release. (more…)