News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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Researchers at Howard Hughes Medical Institute Develop Blood Test That Reveals a Patient’s Viral History; Could Reduce Unnecessary Clinical Laboratory Testing

The VirScan test gives doctors insight into a patient’s lifetime exposure to viruses and thus may be developed into a useful medical laboratory test

Scientists and pathologists are learning that blood is like a time capsule, holding precious information about exposure to viruses over the years—chickenpox at five, mononucleosis at 18, flu at 40. You get the idea.

Now, researchers at Howard Hughes Medical Institute (HHMI)  have found a way to tap that entire data stream, so to speak. An inexpensive blood test, they say, reveals every virus that has passed through the body over time.

New Discoveries Could Lead to a Useful Clinical Laboratory Test

The testing method, called VirScan by researchers, is an efficient alternative to current medical laboratory tests that test for specific viruses one at a time, according to an HHMI news statement about the new technology. (more…)

Florida Rheumatologist Says UnitedHealthcare’s Management Program for Clinical Laboratory Tests Could Jeopardize Patient Care

Miami physician asks why UnitedHealthcare requires use of the BeaconLBS system for authorization for recommended medical laboratory tests that may help identify lymphoma early

In Florida, the confrontation between one of the nation’s largest health insurance corporations and physicians, clinical laboratory managers, and pathologists continues. The source of this confrontation are the restrictive and burdensome requirements for medical laboratory test ordering imposed last fall by UnitedHealthcare (NYSE:UNH) and administered by BeaconLBS, a business division of Laboratory Corporation of America (NYSE:LH).

For Florida rheumatologist Olga Kromo, M.D., UnitedHealthcare’s new decision-support system that physicians are required to use when ordering clinical laboratory tests is highly flawed. (more…)

Clinical Laboratory Scientists Help Crack Newborn Marijuana Mystery

Surprising source of positive medical lab test results was discovered by a special team including pathologists, medical technologists, nurses, and physicians

Some innovative sleuthing by clinical laboratory professionals at University of North Carolina School of Medicine (UNCSM) hospitals has helped solve a marijuana mystery involving neonatal screenings. An unexpected spike in “false positive” cannabis exposure screening results in newborns at the facilities triggered a study by UNCSM scientists.

Revised Screening Protocol Leads to Jump in False Positives

According to a story in MedCity News , in July 2011, the UNCSM clinical laboratories received a call from nurses in the neonatal nursery. They had noticed an increase in positive results in screenings for tetrahydrocannabinol-delta 9-carboxylic acid (THC). THC is the principal psychoactive component of the cannabis plant. (more…)

Aptamer-Based Blood Protein Detection Technology May Soon Be Used By Medical Laboratories in Tests for Cancer, Diabetes, and Other Diseases

Researchers believe that clinical laboratory assays that use aptamers would have multiple advantages when compared to diagnostic tests utilizing anti-bodies

New diagnostic technology has been developed that has the potential to accurately detect such diseases as cancer and diabetes, even when the patient is pre-symptomatic. Not only would medical laboratory tests using this technology be low cost and portable, but some experts think that diagnostic assays using this technology could make it through the regulatory process and be cleared for clinical use in just five years or less.

This highly-sensitive diagnostic technology is able to detect specific proteins in human blood. It was developed by a research team at the University of Toledo in Ohio. Last fall, they published their findings in the Optical Society’s (OSA) open-access journal, Biomedical Optics Express.

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Magnetic Biomarker Chip Spots Cancer Before It Develops

Up to 400 times more sensitive than existing ELISA-based methods

Detecting any of seven cancers in their earliest stages may be feasible through the use of a new biomarker chip that was recently unveiled by scientists from Stanford University’s Center for Magnetic Nanotechnology. To give their biomarker chip increased sensitivity over fluorescent detection methods, the scientists use magnetic technologies to accomplish detection.

Reporting in Proceedings of the National Academy of Sciences (PNAS), lead scientist Shan X. Wang, Ph.D., director of the center and professor of materials science and electrical engineering, says the chip is able to detect very low levels of seven cancers. The biodetection chip is to be marketed by Silicon Valley startup MagArray Inc., of Sunnyvale, California. It detects multiple proteins in blood or DNA strands using magnetic technology similar to how a computer reads a hard drive. Developers say this chip could also be used to diagnose cardiovascular disease and monitor cancer therapy.

(more…)

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