News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups
Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups
Hosted by Robert Michel
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Researchers at Columbia University Report How Exome Sequencing Helped Diagnose Patients with Unknown Disorders

May 14, 2014 | Digital Pathology, Instruments & Equipment, Laboratory Management and Operations, Laboratory News, Laboratory Operations, Laboratory Pathology

More precise diagnoses will encourage pathologists and clinical laboratory professionals to consider using exome sequencing for clinical diagnostic purposes

Having sequenced the exomes of 150 patients to diagnose unknown disorders over the past year, physicians at Columbia University (CU) used that information to make decisive diagnoses in one-third of the cases. It is evidence from one of the nation’s pioneering gene-sequencing programs that such data can improve how physicians identify disease.

Findings from Exome Sequencing Program Noteworthy for Pathologists

Pathologists will find it noteworthy that some of the patients in the exome-sequencing program had been tracked for years at CU without a definitive diagnosis. This is why clinicians at the academic center in New York City see value in exome sequencing for selected patients.

For more than a year, doctors at Columbia University have tested the exome’s capability to provide a correct diagnosis for patients with suspected genetic disorders of unknown origins. The primary goal of the program is to prove that sequencing the exomes of these patients is both clinically useful and cost effective in guiding physicians to a correct diagnosis. (more…)

Preparing the Next Generation of Clinical Pathology Laboratory Managers

May 21, 2010 | Laboratory Hiring & Human Resources, Laboratory Management and Operations, Laboratory News, Laboratory Pathology

The Dark Report and MLO Magazine provide scholarships to the next generation of medical laboratory managers


With so many clinical laboratory managers and administrators of the Baby Boomer generation making retirement plans, it is timely for laboratories to address succession planning in their organization. One essential step is to intensify training for all up-and-coming medical laboratory managers.

As its contribution to this effort, The Dark Report collaborates with MLO Magazine to regularly publicize and offer scholarships to each year’s Executive War College on Laboratory and Pathology Management for a select number of young clinical laboratory managers. This year, one scholarship recipient was Doreen Ng, NCA-CLCP (for Clinical Laboratory Compliance Professional). She is the Manager of Quality Management and Compliance for Baylor College of Medicine Medical Genetics Laboratories in Houston, Texas.

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