Study of Cross-Contamination of Biopsy Specimens in 69 Anatomic Pathology Laboratories Raises Concerns about Test Quality and Patient Safety

Extraneous tissue cross-contamination found in all participating pathology laboratories Cross-tissue contamination, regardless of specimen volume or how frequently reagents were changed Pathologists and histotechnologists have long known that traditional methods of processing tissue for diagnosis have the potential to cross-contaminate human biopsy specimens. This risk to patient safety and diagnostic accuracy was accepted over the decades because of the limitations of technology and inability...

Revisiting the Clinical Pathology Lab’s Problem of Floaters and Other Contaminates

As automation transforms the manual work processes in the histopathology laboratory, “floaters” may become a thing of the past Any histotechnologist and pathologist familiar with the manual work processes commonly in use in histopathology laboratories knows about “floaters.” These are the pesky artifacts that are a consequence of the common practice of manually processing tissue through the series of H&E linear baths required for the proper staining of these samples prior to analysis by...