Innovative Programs by Geisinger Health and Kaiser Permanente Are Moving Providers in Unexplored Directions in Support of Proactive Clinical Care

These initiatives are a call-to-action for clinical laboratories to contribute their expertise in support of wellness programs Two of the largest healthcare systems in America are moving in non-traditional directions to proactively address certain healthcare populations. Most recently, Kaiser Permanente announced it will be investing millions of dollars to tackle homelessness and the disease outbreaks associated with it. The health system is even investing in a housing complex in Oakland,...

Multiomics Genetic Research May Give Clinical Laboratories New Capabilities in the Diagnosis and Treatment of Cancers in Children

Three-platform genetic sequencing offers hope for improved pediatric oncology diagnostics and precision medicine therapies Dark Daily has long predicted that multiomics will someday play an important role in clinical laboratory diagnostic medicine. Now, new research from St. Jude Children’s Research Hospital provides early evidence of that prediction coming to fruition.  Scientists at St. Jude’s have discovered that performing different genetic tests on pediatric cancer patients, and then...

Aspenti Health Takes Home Grand Prize in Nation’s First Clinical Lab 2.0 ‘Shark Tank’ Competition Showcasing Added-Value Clinical Success Stories

Vermont-based clinical laboratory company integrates social determinants of health (SDH) with lab data to help doctors at University of Vermont Health Network better manage their opioid patients Aspenti Health, a full-service diagnostic laboratory specializing in toxicology screening, has won the nation’s first ever Clinical Lab 2.0 “Shark Tank”! The competition was held May 2, 2019, in conjunction with the 24th Annual Executive War College on Lab and Pathology Management in New Orleans. The...

Researchers at Massachusetts General Hospital Identify Ways That CRISPR DNA Base Editors Sometimes Unintentionally Alter RNA

These “off-target” genetic alterations demonstrate that certain CRISPR base editors need further refinement in a research finding of interest to pathologists Could CRISPR DNA-editing technology unintentionally effect RNA as well? A new study conducted at Massachusetts General Hospital (MGH) suggests that it can. Clinical laboratories doing genetic testing will want to understand why this research implies that refinements to CRISPR may be needed for it to be accurate in therapeutic...

MIT Researchers Link Acidic Environments to Cancer Tumor Growth and Invasion of Healthy Tissue; Might Be Useful Diagnostic Element for Pathologists

Methods that target the causes of acidity could become part of precision medicine cancer treatments and therapies Researchers at Massachusetts Institute of Technology (MIT) have found that acidic environments enable tumor cells to strengthen through protein production. And that when acidic surfaces extend beyond a tumor’s interior, and come into contact with healthy tissue, cancer can spread. The results of their study will interest anatomic pathologists who review tissue biopsies to diagnose...

Medical Genome Reference Bank Uses Whole-Genome Sequencing to Add 4,000 Healthy Older Adults to Its Huge Database

The resulting genomic dataset may provide useful diagnostic insights that can be used by clinical laboratory and pathology professionals to learn how and why some people age with good health Why do some seniors age in good health and other seniors suffer with multiple chronic conditions? A new genetic database is using whole-genomic sequencing (WGS) to answer that question in ways that may benefit medical laboratories. Because of the rapid aging of populations in the United States and other...